LMA - Laboratoire de Mécanique et d’Acoustique

Philippe LASAYGUES

Ingénieur de Recherche, CNRS
HDR


Research Engineer

Diplômes/Degrees/Qualification

- Docteur en Mécanique, spécialité Acoustique - Aix Marseille Université
Ph-D degrees in Acoustic, Aix-Marseille University

- Habilitation à diriger des recherches (HDR) - Aix Marseille Université
Award of the French Habilitation Qualification, Aix-Marseille University

Groupe : Ultrasons Médicaux
Medical Ultrasounds (USMED)

Thèmes de recherche/Research Interests

- Propagation d’ondes élastique et ultrasonore (problèmes directs et inverses), imagerie ultrasonore, tomographie ultrasonore ;
• Ultrasound, Elastic and Ultrasonic wave propagation, Ultrasonic imaging, Ultrasound computed tomography - USCT ;

- Ultrasons pour la thérapie, Stimulation ultrasonore de cellules (osseuses), Mécanotransduction par ondes acoustiques, Modélisation et caractérisation expérimentale de champs d’ondes.
• Ultrasound for therapy, Ultrasound stimulation of (bone) cells, Mechanotransduction by acoustic waves, Experimental modeling and characterization of wave fields.

- Caractérisation de tissus biologiques, de milieux naturels et de matériaux manufacturés pour les applications d’ingénierie biomédicale et de contrôle non destructif.
• Characterization of biological and natural tissues and materials, as well as manufactured objects for biomedical engineering and non-destructive applications.

- Traitement du signal et expérimentation ultrasonore, Optimisation, Modélisation expérimentale ; Antennes acoustiques, Transducteurs et capteurs ultrasonores.
• Ultrasonic signal processing and experimentation, Optimization, Experimental modeling ; Acoustic antennas, Ultrasonic transducers and sensors.

En cours / In progress

- Linear and nonlinear Ultrasound Computed Tomography-USCT :

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G2AMI project

- ln vitro mechanotransduction triggered by ultrasound :

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INVICT-US Project (ANR)

- Modeling and ultrasonic imaging for bone identification in archaeo-paleontology :

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ARCHé-US Project (Institut ARKAIA)

Collaborations

Aix & Marseille
- Institut de Recherche sur les Phénomènes Hors Equilibre (IRPHE), UMR 7342, Aix Marseille Univ, CNRS, Centrale Marseille, Marseille
- Département de radiologie pédiatrique et prénatale, Hôpital d’enfants "La Timone", APHM, Marseille
- Laboratoire Méditerranéen de Préhistoire Europe-Afrique (LAMPEA), UMR 7269, Aix Marseille Univ, CNRS, Aix en Provence

France
- Laboratoire d’analyse et d’architecture des systèmes (LAAS-CNRS), UPR 8001, CNRS, Toulouse
- Institut de Biologie Valrose (IBV), UMR 7277, Université Côte d’Azur, CNRS, Inserm, Nice
- CIRAD, UR BioWooEB, Univ Montpellier, Montpellier
- Institut Clément Ader (ICA), UMR 5312, Univ Fédérale Toulouse Midi-Pyrénées, Tarbes
- Cultures et Environnements Préhistoire, Antiquité, Moyen Âge (CEPAM), UMR 7264, CNRS, Univ Cote d’Azur, Nice

International
- Dept. of Mechanical and Mechatronics Engineering, Universidad Nacional de Colombia, Bogotá, Colombia
- Agencia de Renovación del Territorio, Bogotá, Colombia
- Laboratoire d’Électronique et de Microélectronique, Université de Monastir, Monastir, Tunisie

Direction de thèses / PhD supervisor

- 2020-2023, DOVERI Elise, Perspectives en imagerie et thérapie ultrasonores de pathologies osseuses chez l’enfant, AMU (codir. C. Baron, IRPHE)

- 2021-2024, HUERTAS Juan Felipe, Etude des cellules sous sollicitation électromagnétique et acoustique, Université Nationale de Colombie, Bogota, Colombie (codir. F. Prieto Ortiz, GAUNAL, Bogota)

Affiliations professionnelles / Professional Affiliations

- European Acoustics Association (EAA)
Board of the Technical Committee on Ultrasound (TC-ULT) ;

- Société Française d’Acoustique (SFA)
French Acoustical Society
GAPSUS : Acoustique Physique, Sous-marine et Ultrasonore
Physical acoustics, Underwater acoustics, ultrasonic group
https://sfa.asso.fr/thematiques/gro...)

Publications

ORCID : http://orcid.org/0000-0003-2700-7774

- Papers in refereed journal

1. Majnooni M, Doveri E, Baldisser J, Long V, Houles J, Scimeca JC, et al. Anti-reflection cover to control acoustic intensity in in vitro low-intensity ultrasound stimulation of cells. Acta Acust. 2022 ;6:11.

2. Majnooni M, Lasaygues P, Long V, Scimeca JC, Momier D, Rico F, et al. Monitoring of in-vitro ultrasonic stimulation of cells by numerical modeling. Ultrasonics. 2022 Aug ;124:106714.

3. Cailly W, Walaszek H, Brzuchacz S, Zhang F, Lasaygues P. Assessment of Long-Range Guided-Wave Active Testing of Storage Tanks. J Phys Conf Ser. 2021 Jan ;1761:012008.

4. Cailly W, Walaszek H, Brzuchacz S, Zhang F, Lasaygues P. Assessment of qualitative and quantitative S 0 guided wave tomography of sharp thickness loss defects in the isotropic membrane regime. J Acoust Soc Am. 2021 Mar ;149(3):1475–87.

5. Doveri E, Sabatier L, Long V, Lasaygues P. Reflection-Mode Ultrasound Computed Tomography Based on Wavelet Processing for High-Contrast Anatomical and Morphometric Imaging. Appl Sci. 2021 Oct 9 ;11(20):9368.

6. Espinosa L, Doveri E, Bernard S, Monteiller V, Guillermin R, Lasaygues P. Ultrasonic Imaging of High-contrasted Objects Based on Full-waveform Inversion : Limits under Fluid Modeling. Ultrason Imaging. 2021 Mar ;43(2):88–99.

7. Cailly W, Walaszek H, Brzuchacz S, Zhang F, Lasaygues P. Pipe two-phase flow non-invasive imaging using Ultrasound Computed Tomography : A two-dimensional numerical and experimental performance assessment. Flow Meas Instrum. 2020 Aug ;74:101784.

8. Espinosa L, Prieto F, Brancheriau L, Lasaygues P. Quantitative parametric imaging by ultrasound computed tomography of trees under anisotropic conditions : Numerical case study. Ultrasonics. 2020 Mar ;102:106060.

9. Espinosa L, Brancheriau L, Cortes Y, Prieto F, Lasaygues P. Ultrasound computed tomography on standing trees : accounting for wood anisotropy permits a more accurate detection of defects. Ann For Sci. 2020 Sep ;77(3):68.

10. Lefevre E, Baron C, Gineyts E, Bala Y, Gharbi H, Allain JM, et al. Ultrasounds could be considered as a future tool for probing growing bone properties. Sci Rep. 2020 Dec ;10(1):15698.

11. Cailly W, Walaszek H, Brzuchacz S, Zhang F, Lasaygues P. Low-Frequency Guided Wave Quantitative Reconstruction of Corrosion in Plates, 1D Diffraction Problem. Acta Acust United Acust. 2019 Dec ;105(6):970–86.

12. Espinosa L, Prieto F, Brancheriau L, Lasaygues P. Effect of wood anisotropy in ultrasonic wave propagation : A ray-tracing approach. Ultrasonics. 2019 Jan ;91:242–51.

13. Semaan M, Mora P, Bernard S, Launay F, Payan C, Lasaygues P, et al. Assessment of elastic coefficients of child cortical bone using resonant ultrasound spectroscopy. J Mech Behav Biomed Mater. 2019 Feb ;90:40–4.

14. Espinosa L, Bacca J, Prieto F, Lasaygues P, Brancheriau L. Accuracy on the Time-of-Flight Estimation for Ultrasonic Waves Applied to Non-Destructive Evaluation of Standing Trees : A Comparative Experimental Study. Acta Acust United Acust. 2018 May 1 ;104(3):429–39.

15. Espinosa L, Brancheriau L, Prieto F, Lasaygues P. Sensitivity of Ultrasonic Wave Velocity Estimation Using the Christoffel Equation for Wood Non-Destructive Characterization. Bioresources. 2018 ;13(1):918–28.

16. Lasaygues P, Arciniegas A, Espinosa L, Prieto F, Brancheriau L. Accuracy of coded excitation methods for measuring the time of flight : Application to ultrasonic characterization of wood samples. Ultrasonics. 2018 Sep ;89:178–86.

17. Bernard S, Monteiller V, Komatitsch D, Lasaygues P. Ultrasonic computed tomography based on full-waveform inversion for bone quantitative imaging. Phys Med Biol. 2017 Aug 9 ;62(17):7011–35.

18. Bala Y, Lefèvre E, Roux JP, Baron C, Lasaygues P, Pithioux M, et al. Pore network microarchitecture influences human cortical bone elasticity during growth and aging. J Mech Behav Biomed Mater. 2016 Oct ;63:164–73.

19. Diong ML, Roueff A, Lasaygues P, Litman A. Impact of the Born approximation on the estimation error in 2D inverse scattering. Inverse Probl. 2016 Jun 1 ;32(6):065006.

20. Metwally K, Lefevre E, Baron C, Zheng R, Pithioux M, Lasaygues P. Measuring mass density and ultrasonic wave velocity : A wavelet-based method applied in ultrasonic reflection mode. Ultrasonics. 2016 Feb ;65:10–7.

21. Elayouch A, Addouche M, Lasaygues P, Achaoui Y, Ouisse M, Khelif A. How diffraction limits ultrasonic screening in phononic plate composed of a periodic array of resonant slits. Comptes Rendus Phys. 2016 May ;17(5):518–23.

22. Berteau JP, Gineyts E, Pithioux M, Baron C, Boivin G, Lasaygues P, et al. Ratio between mature and immature enzymatic cross-links correlates with post-yield cortical bone behavior : An insight into greenstick fractures of the child fibula. Bone. 2015 Oct ;79:190–5.

23. Diong ML, Roueff A, Lasaygues P, Litman A. Precision analysis based on Cramer–Rao bound for 2D acoustics and electromagnetic inverse scattering. Inverse Probl. 2015 Jul 1 ;31(7):075003.

24. Lefèvre E, Lasaygues P, Baron C, Payan C, Launay F, Follet H, et al. Analyzing the anisotropic Hooke׳s law for children׳s cortical bone. J Mech Behav Biomed Mater. 2015 Sep ;49:370–7.

25. Lefèvre E, Lasaygues P, Baron C, Payan C, Follet H, Pithioux M. Ultrasonic assessment of diagonal stiffness coefficients in children cortical bone. Comput Methods Biomech Biomed Engin. 2015 Oct 9 ;18(sup1):1978–9.

26. Rouyer J, Mensah S, Vasseur C, Lasaygues P. The benefits of compression methods in acoustic coherence tomography. Ultrason Imaging. 2015 Jul ;37(3):205–23.

27. Arciniegas A, Brancheriau L, Lasaygues P. Tomography in standing trees : revisiting the determination of acoustic wave velocity. Ann For Sci [Internet]. 2014 Aug 13 [cited 2014 Oct 23] ; Available from : http://link.springer.com/10.1007/s1...

28. Arciniegas A, Prieto F, Brancheriau L, Lasaygues P. Literature review of acoustic and ultrasonic tomography in standing trees. Trees [Internet]. 2014 Aug 6 [cited 2014 Oct 21] ; Available from : http://link.springer.com/10.1007/s0...

29. Arciniegas A, Brancheriau L, Gallet P, Lasaygues P. Travel-Time Ultrasonic Computed Tomography Applied to Quantitative 2-D Imaging of Standing Trees : A Comparative Numerical Modeling Study. Acta Acust United Acust. 2014 Nov 1 ;100(6):1013–23.

30. Berteau JP, Baron C, Pithioux M, Launay F, Chabrand P, Lasaygues P. In vitro ultrasonic and mechanic characterization of the modulus of elasticity of children cortical bone. Ultrasonics. 2014 Jul ;54(5):1270–6.

31. Cucciati G, Auffray E, Bugalho R, Cao L, Vara ND, Farina F, et al. Development of ClearPEM-Sonic, a multimodal mammography system for PET and Ultrasound. J Instrum. 2014 Mar 6 ;9(03):C03008–C03008.

32. Guillermin R, Lasaygues P, Rabau G. Quantitative non-linear ultrasonic imaging of targets with high acoustic impedance contrast-Application to bone imaging. J Acoust Soc Am. 2014 Apr ;135(4):2268.

33. Pizzichemi M, Bugalho R, Cao L, Cucciati G, Di Vara N, Farina F, et al. 157 : ClearPEM-Sonic : a multimodal PET-ultrasound mammography system. Radiother Oncol. 2014 Feb ;110:S76–7.

34. Guillermin R, Lasaygues P, Rabau G, Lefebvre JP. Quantitative non-linear ultrasonic imaging of targets with significant acoustic impedance contrast—An experimental study. J Acoust Soc Am. 2013 Aug ;134(2):1001–10.

35. Berteau JP, Pithioux M, Baron C, Gineyts E, Follet H, Lasaygues P, et al. Characterisation of the difference in fracture mechanics between children and adult cortical bone. Comput Methods Biomech Biomed Engin. 2012 ;15 Suppl 1:281–2.

36. Berteau JP, Pithioux M, Follet H, Guivier-Curien C, Lasaygues P, Chabrand P. Computed tomography, histological and ultrasonic measurements of adolescent scoliotic rib hump geometrical and material properties. J Biomech. 2012 Sep 21 ;45(14):2467–71.

37. Rouyer J, Mensah S, Franceschini E, Lasaygues P, Lefebvre JP. Conformal ultrasound imaging system for anatomical breast inspection. IEEE Trans Ultrason Ferroelectr Freq Control. 2012 Jul ;59(7):1457–69.

38. Berteau JPh, Lasaygues Ph, Pithioux M, Chabrand P. Adolescent idiopathic scoliosis young female rib hump : normative biomechanical data study. Comput Methods Biomech Biomed Engin. 2011 Aug ;14(sup1):47–8.

39. Jun Dang, Frisch B, Lasaygues P, Dachun Zhang, Tavernier S, Felix N, et al. Development of an Anthropomorphic Breast Phantom for Combined PET, B-Mode Ultrasound and Elastographic Imaging. IEEE Trans Nucl Sci. 2011 Jun ;58(3):660–7.

40. Lasaygues P. Ultrasonic discrimination and modelling for crack-tip echoes. Nondestruct Test Eval. 2011 Mar ;26(1):67–85.

41. Loosvelt M, Lasaygues P. A Wavelet-Based Processing method for simultaneously determining ultrasonic velocity and material thickness. Ultrasonics. 2011 Apr ;51(3):325–39.

42. Jun Dang, Lasaygues P, Dachun Zhang, Tavernier S, Felix N, Frisch B, et al. Development of breast anthropomorphic phantoms for combined PET-ultrasound elastography imaging. In IEEE ; 2009 [cited 2014 Oct 21]. p. 3088–92. Available from : http://ieeexplore.ieee.org/lpdocs/e...

43. Lasaygues P, Le Marrec L. Ultrasonic reflection tomography vs. canonical body approximation : experimental assessment of an infinite elastic cylindrical tube. Ultrason Imaging. 2008 Jan ;30(1):29–43.

44. Brancheriau L, Lasaygues P, Debieu E, Lefebvre JP. Ultrasonic tomography of green wood using a non-parametric imaging algorithm with reflected waves. Ann For Sci. 2008 Jan ;65(7):712–712.

45. Franceschini E, Mensah S, Le Marrec L, Lasaygues P. An optimization method for quantitative impedance tomography. IEEE Trans Ultrason Ferroelectr Freq Control. 2007 Aug ;54(8):1578–88.

46. Lasaygues P. Assessing the cortical thickness of long bone shafts in children, using two-dimensional ultrasonic diffraction tomography. Ultrasound Med Biol. 2006 Aug ;32(8):1215–27.

47. Lasaygues P, Guillermin R, Lefebvre JP. Distorted Born diffraction tomography applied to inverting ultrasonic field scattered by noncircular infinite elastic tube. Ultrason Imaging. 2006 Oct ;28(4):211–29.

48. Le Marrec L, Lasaygues P, Scotti T, Tsogka C. Efficient shape reconstruction of non-circular tubes using broadband acoustic measurements. Acta Acust United Acust. 2006 ;92(3):355–61.

49. Lasaygues P, Ouedraogo E, Lefebvre JP, Gindre M, Talmant M, Laugier P. Progress towards in vitro quantitative imaging of human femur using compound quantitative ultrasonic tomography. Phys Med Biol. 2005 Jun 7 ;50(11):2633–49.

50. Lasaygues P, Tanne D, Mensah S, Lefebvre JP. Circular Antenna for Breast Ultrasonic Diffraction Tomography. Ultrason Imaging. 2002 Jul ;24(3):177–89.

51. Ouedraogo E, Lasaygues P, Lefebvre JP, Gindre M, Talmant M, Laugier P. Contrast and velocity ultrasonic tomography of long bones. Ultrason Imaging. 2002 Jul ;24(3):139–60.

52. Pithioux M, Lasaygues P, Chabrand P. An alternative ultrasonic method for measuring the elastic properties of cortical bone. J Biomech. 2002 Jul ;35(7):961–8.

53. Lasaygues P, Lefebvre JP. Cancellous and cortical bone imaging by reflected tomography. Ultrason Imaging. 2001 Jan ;23(1):55–70.

54. Guillermin R, Lasaygues P, Sessarego JP, Wirgin A. Imaging an object buried in the sediment bottom of a deep sea by linearized inversion of synthetic and experimental scattered acoustic wavefields. Inverse Probl. 2000 Dec 1 ;16(6):1777–97.

55. Lasaygues P, Lefebvre JP. Deconvolution in Low Frequency Ultrasonic Reflection Tomography. In : Thompson DO, Chimenti DE, editors. Review of Progress in Quantitative Nondestructive Evaluation [Internet]. Boston, MA : Springer US ; 1999 [cited 2014 Oct 21]. p. 943–9. Available from : http://link.springer.com/10.1007/97...

56. Lasaygues P, Lefebvre JP, Mensah S. High resolution low frequency ultrasonic tomography. Ultrason Imaging. 1997 Oct ;19(4):278–93.

57. Lefebvre, Lasaygues. Wavelet analysis for ultrasonic crack detection and modelization. In IEEE ; 1994 [cited 2014 Oct 21]. p. 1143–6 vol.2. Available from : http://ieeexplore.ieee.org/lpdocs/e...

- Book chapters

J.-P. Lefebvre, P. Lasaygues et S. Mensah, Tomographie acoustique, Matériaux & Acoustique, III, 4.7, Hermes Science Publishing Ltd, 2005, pp.351-378

2- J.-P. Lefebvre, P. Lasaygues et S. Mensah. La tomographie acoustique. Mécanique et Ingénierie des Matériaux. Hermès (Paris), 2006, pp. 351–378

3- J.-P. Lefebvre, P. Lasaygues et S. Mensah. Acoustic Tomography, Ultrasonic Tomography, chapter 35-Materials and Acoustics Handbook, M. Bruneau & C. Potel Eds, ISTE&Wiley, 2009, pp.887-906

4- P. Lasaygues, R. Guillermin and J.-P. Lefebvre, Ultrasonic Computed Tomography, chapter 18-Bone Quantitative Ultrasound, P. Laugier & G. Haiat Eds, Springer, 2011, pp.441-459

5- P. Lasaygues, L. Espinosa, S. Bernard, P. Petit, and R. Guillermin, “Ultrasound Computed Tomography,” in Bone Quantitative Ultrasound New Edition, Springer., vol. 11, Paris, 2021, pp. 1–36.

6- C. Baron, H. Follet, M. Pithioux, C. Payan, and P. Lasaygues, “Assessing the elasticity of child cortical bone,” in Bone Quantitative Ultrasound New Edition, P. Laugier&Q. Grimal., vol. 14, Paris, 2021, pp. 1–29.

- Thesis

1- Etude de l’écho d’une fissure, traitement de signaux par analyse en ondelettes en contrôle non destructif, Thèse de l’Université de la Méditerranée (Aix-Marseille II), 1992 https://www.theses.fr/1992AIX22068

2- Tomographie ultrasonore osseuse : Caractérisation de la diaphyse des os par inversion d’un champ acoustique diffracté, Habilitation à diriger des Recherches, Université de la Méditerranée (Aix-Marseille II), 2006 https://tel.archives-ouvertes.fr/te...

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